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This book explains the fundamental principles and focuses on those topics that students have identified as being most difficult to grasp. Part I discusses general principles such as pharmacokinetics and drug metabolism and elimination. Parts II through VI present various classes of drugs such as autonomics, drugs that affect the cardiovascular system, drugs that affect the central nervous system, chemotherapeutic agents, drugs that affect the endocrine system, and miscellaneous drugs. The third edition will include a new chapter on poisoning/toxicology and several new classes of drugs, such as protease inhibitors for HIV and angiotensin II receptor blockers for HTN.